TUBEX® TF

Rapid Typhoid Detection.

IDL Biotech’s TUBEX® TF is a rapid and sensitive in vitro diagnostic test for the detection of acute typhoid fever, a disease caused by Salmonella typhi. 

TUBEX® TF

TUBEX® TF can easily be performed in any laboratory or field setting, and with a result within 10 minutes. A positive TUBEX® TF result, together with typical clinical symptoms, is a strong indication of acute typhoid fever.

The test is a semiquantitative assay based on IMBI® technology (Inhibition Magnetic Binding Immunoassay), a simple assay technology based on visual interpretation.

A complement product to TUBEX® TF is TUBEX® TF Wash which is recommended to be used for the analysis of colored serum samples.

IDL Biotech is the legal manufacturer of TUBEX® TF and TUBEX® TF Wash.

tubex

Find more information

TUBEX® TF is characterized by high sensitivity and specificity. TUBEX® TF can be performed in any laboratory environment and the result is ready within 10 minutes.

Download the broschure

Clinical evaluation

In a comparative study in the Philippines, Kawano and co-workers evaluated four antibody detection tests for typhoid fever. The sensitivity of TUBEX® TF was 95% at a specificity of 80%. In this study TUBEX® TF performed best among other analysed tests. TUBEX® TF has been clinically evaluated on more than 5000 patients in different endemic settings, showing consistent performance across multiple continents.  

References for TUBEX TF

Tarupiwa, A., Tapera, S., Mtapuri-Zinyowera, S., Gumbo, P., Ruhanya, V., Gudza-Mugabe, M., Majuru, N.M., Chinombe, N.: Evaluation of TUBEX TF and onsite Typhoid IgG/IgM Combo Rapid tests to detect Salmonella enterica serovar typhi infection during a typhoid outbreak in Harare, Zimbabwe. BMC Research Notes 2015;8.

Lelei, Walter, Andrew K. Nyerere, Robert S. Onsare and Samuel M Kariuki. “Performance of TUBEX® TF IgM Antibody Test Against Culture to Detect Typhoid Fever Among Hospitalized Patients in Nairobi County.” Journal of Biology, Agriculture and Healthcare (2019): n. pag.

Kawano RL, Leano SA, Agdamag D.M.: Comparison of serological test kits for diagnosis of typhoid fever in the Philippines. J Clin Microbiol 2007; 45: 246-247.

Rahman, M., Siddique, A.K., Tam, F.C.-H., Sharmin, S., Rashid, H., Iqbal, A., Ahmed, S., Nair, G.B., Chaignat, C.-L., Lim, P.-L.: Rapid detection of early typhoid fever in endemic community children by the TUBEX® O9-antibody test. Diagn Microbiol Infect Dis 2007; 58: 275-281.

Olsen, S.J., Pruckler, J., Bibb, W., Nguyen, T.M., Tran, M.T., Nguyen, T.M., Sivapalasingam, S., Gupta, A., Phan, T.P., Nguyen, T.C., Nguyen, V.C., Phung, D.C., Mintz, E.D.: Evaluation of rapid diagnostic tests for typhoid fever. J Clin Microbiol 2004; 42: 1885-1889.

Bundalian, R., Jr, Valenzuela, M., & Tiongco, R. E. (2019). Achieving accurate laboratory diagnosis of typhoid fever: a review and meta-analysis of TUBEX® TF clinical performance. Pathogens and global health, 113(7), 297–308.

Khanna, A., Khanna, M., Karamjit S.G. : Comparative evaluation of TUBEX TF for typhoid fever in endemic area. J of Clin. And Diagn Res. 2015 Nov, Vol-9(11): DC14-C`DC17.

Tam FCH., Leung DTM., Ma CH., Lim P-L.: Modification of the Tubex typhoid test to detect antibodies directly from haemolytic serum and whole blood. J Medical Microbiol 2008; 57: 1349-1353.

Lim, P-L., Tam, F., Cheong, Y-M., Jegathesan, M.: One-step 2-minute test to detect typhoid-specific antibodies based on particle separation in tubes. J Clin Microbiol 1998; 36: 2271-2278.

WHO. Background document: The diagnosis, treatment and prevention of typhoid fever. 2003; 11-16. WHO/V&B/03.07.

Bacteriology

An effective typhoid test

Typhoid fever is water and food-borne infectious disease caused by the bacterium, Salmonella enterica. IDL Biotechs product TUBEX® TF, is a rapid and sensitive in vitro diagnostic test for the detection of acute typhoid fever.

Read more about bacteriology
Oncology

Diagnostics for oncology

Cancer is one of the leading causes of death worldwide, despite advancing knowledge. To improve cancer patient management, there is a clear need for efficient diagnostics tools to capture this critical clinical data.

Read more about oncology
Investors

We are listed on NASDAQ First North Growth Market.

We want to be the obvious choice within our segment in the markets where we are established. The market for our products is large and we are a smaller player with significant growth potential so far. AroCell is unique for a company of this size.

Read more about investing