News


AroCell AB (publ) signs Letter of Intent with Korean-based company, Green Cross Cell Corporation.

The companies have agreed to enter into a collaboration for the clinical development of TK 210 ELISA as a complementary biomarker related to Green Cross Cell’s therapeutic products and methods and distribution rights for AroCell TK 210 ELISA.

The TK 210 ELISA test measures TK1 protein levels for valuable information about the condition of cancer patients. The test may provide important information for the prognosis and optimization of treatment strategy.

“Developing medicines, especially new drugs, necessitates investment of time and capital. It is hard to achieve, without the beliefs and willingness to cure diseases.” Says Duck-joo Lee, CEO at Green Cross Cell. Since the inception of indigenous development of cell therapy products in 2002, Green Cross Cell has focused on research and development, determined to deliver hope to patients and their families. As a result, in 2007, Green Cross Cell acquired the product license of an anti-cancer immunotherapy product for liver cancer, for the first time in the world.

As a next-generation anticancer drug expressing superior therapeutic effects to conventional anticancer drugs having few side effects, Green Cross Cell’s Immunotherapy not only kills cancer cells, but also enhances the human immune system, through which a comprehensive therapeutic effect is expected.

AroCell will have a positive role as a reliable partner for Green Cross Cell in the world’s biopharmaceutical market striving to become a global leader in the field of cell therapy through its intensive R&D studies. Green Cross Cell has recently initiated a process to enter the US market and has established high level collaboration with the State of Maryland.

“This will have a great potential also for AroCell and the TK 210 ELISA biomarker since the test will be a very strong candidate in these studies” says Duck-joo Lee, CEO at Green Cross Cell.

“We are very excited about this collaboration with Green Cross Cell, not only the distribution of our product but also the plan to use TK 210 ELISA as their primary biomarker for their therapeutic drugs and treatments” says Jan Stålemark, CEO at AroCell. Green Cross Cell has one of the most promising therapies for patients with very challenging cancers such as liver cancer, colorectal and glioblastoma brain cancer.

 

 AroCell is obliged to make public this information pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication through Jan Stålemark, at 08:55 CET on 22 November 2017.

 

 About AroCell
AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure Thymidine Kinase 1 (TK1) protein levels in a blood sample. The TK 210 ELISA test provides valuable information mainly about the condition of cancer patients. This may help clinicians to optimize treatment strategies and estimate the risk of recurrence of tumor disease during the monitoring of the disease. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

GCCell_AroCell AB_Press Release Nov 22, 2017

GCCell_AroCell AB_PM_20171122_SV

AroCell AB (publ) Interim Report, Q3 2017

AroCell AB (publ)

Reporting period 1 July – 30 September 2017

  • Net sales were 0 (46) KSEK
  • Losses after financial items were – 3,678 (- 2,590) KSEK
  • Earnings per share were – 0.12 (- 0.09) SEK
  • Cash flow from operating activities was – 4,227 (- 784) KSEK
  • Cash flow from investing activities was 0 (- 2,376) KSEK
  • Cash flow for the period was – 4,227 (-3,160) KSEK

Interim report 1 January – 30 September 2017
• Net sales were 293 (46) KSEK
• Losses after financial items were – 11,510 (- 7,395) KSEK
• Cash flow for the period was -12,656 (-10,861) KSEK
• Earnings per share were – 0.40 (- 0.26) SEK

Revenues and expenses July – September 2017 (2016) KSEK

Sales for the period were 0 (46). Expenses were 3,678 (2,590). Taking into account capitalization of R&D, total expenses for the same period in 2016 amounted to 5,012. As the product has been fully developed and CE-marked, R&D expenses are no longer capitalized. R&D expenses are loaded with depreciation of intangible assets 1 119 (0). Total cash flow for the period was -4,227 (-3,160). Cash at the end of the period was 20,196.

Revenues and expenses January – September 2017 (2016) KSEK

Sales for the period were 293 (46). Expenses were 11,510 (7,394). Taking into account capitalization of R&D, total expenses for the same period in 2016 amounted to 14,791. As the product has been fully developed and CE-marked, R&D expenses are no longer capitalized. R&D expenses are loaded with depreciation of intangible assets 1 119 (0). According to plan marketing and sales expenses have increased which reflects our ambition to get TK 210 ELISA test Kit to the market. Total cash flow for the period was -12,656 (-10,681). Cash at the end of the period was 20,196.

AroCell is obliged to make public this information pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication through Jan Stålemark, at 08:45 CET on 22 November 2017.

About AroCell
AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure Thymidine Kinase 1 (TK1) protein levels in a blood sample. The TK 210 ELISA test provides valuable information mainly about the condition of cancer patients. This may help clinicians to optimize treatment strategies and estimate the risk of recurrence of tumor disease during the monitoring of the disease. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

 

CEO Comments

We are making good progress and we feel confident that TK 210 ELISA will become a very valuable biomarker in the care of patients with cancer. Our route to success is based on a strategy which can be divided in three main focus areas.

 

Our first focus area is the clinical development and validation of TK 210 ELISA. This is critical for achieving acceptance by researchers in drug development and clinical research organizations (CROs). Results from clinical studies and experimental studies are necessary to prove utility, both in research models and clinical practice. During the quarter, we have presented and communicated three important study results raising our comfort level of the relevance and importance of TK 210. The clinical validation remains a priority to ensure customer acceptance and long-term growth. Recent results in studies which give additional and new evidence that TK 210 ELISA provides vital information about how our test can be used in drug development and monitoring treatment response of cancer. The three most recent studies:

  • Breast cancer, PROMIX – “Quantification of cell loss in breast cancer during neoadjuvant treatment (NACT) assessed by serum thymidine kinase protein concentrations (sTK1)” at ESMO Asia Singapore, November 2017
  • Research study – Novel method for studying the in-vitro effects of anti-cancer agents: the assay of thymidine kinase 1 (TK1) in cell culture utilising AroCell TK 210 ELISA presented at NCRI UK, Liverpool, November 2017
  • Prostate cancer -” AroCell TK 210 ELISA may complement pro PSA and the prostate health index in differentiating non-cancerous from cancerous conditions in prostate disease” presented at NCRI UK, Liverpool, November 2017

 

These studies provide valuable evidence on how our TK 210 ELISA test can be used in different types of applications, experimental models in the research area for drug development and clinical studies we are now able to better attract the interest from both pharmaceutical and IVD companies with automated systems.

 

Our second priority is the licensing and tech transfer of our TK 210 ELISA technology and know-how. Our goal here is to offer our intellectual property, know-how and material to other companies to implement on their automated systems. This could enable our TK 210 ELISA test to become one of the most used biomarkers in the market. We need to show clinical and research applicability in several areas to motivate companies to negotiate with us to get access to TK 210 ELISA through a licensing agreement. We can, with clinical and experimental results, increase the interest for our technology and know-how.

 

Our third focus area is the commercialization of TK 210 ELISA product to drive demand and revenue. Our clinical development and validation strategy supports this and will provide the evidence we need to show how our product can be used in multiple applications, research areas and clinical practice by healthcare professionals.

 

We will continue to validate and promote the use of the TK 210 ELISA test and with the goal to make it one of the most used biomarkers in the treatment of cancer.

 

Jan Stålemark

CEO

 

 

Essential risks

Financial risks

AroCell’s business activities are based on external financing. To date, the company has been successful in obtaining financing, but there are not guarantees of this happening in the future in a way that is advantageous to the company’s shareholders. A sufficiently serious failure in future financing may affect the company’s development and market value.

Development and production risks

Development and transfer to production are always associated with risks. A product manufactured at production scale does not always display the same characteristics as one manufactured at research scale. Developing future products may also prove to be more complicated and take longer than expected.

 

Commercialization risks

There is always a risk that the products AroCell has developed will not achieve the expected positive reception on the market and that the product will need longer time to gain acceptance. Particularly in the early stages, the quantity of products sold may then be lower and the time it takes to establish the product on the market may be longer than the company allowed for in its sales estimates.

 

Currency risks

The company expenses are partially based in Euro, and this means that there is a risk that weakening of the Swedish krona against the Euro may lead to increased expenses for the company. A portion of the sales proceeds in future can be associated with currencies from other countries, which means that there is a risk that if the Swedish krona becomes stronger to other currencies, this may lead to decreased profits for the company in SEK.

 

In addition, there are risks associated with patent security and how the market assesses studies, approvals and certifications. Taking risk factors into consideration in decision processes and when designing routines and drawing up documentation means that the risks are assessed and their effects can be minimized, and to some extent, avoided.

 

The share

AroCell AB (publ) was listed on Nasdaq First North, Stockholm, June 30, 2016 under AROC.

On March 31, 2017, there were 28 674 506 shares (quota value SEK 0.10).

 

Accounting principles

This Interim Report has been prepared in accordance with the Swedish law: Årsredovisningslagen and Bokföringsnämndens allmänna råd BFNAR 2012:1 Årsredovisning och Koncernredovisning (K3).

 

Report review

This interim report has not been reviewed by the company´s auditor.

 

Contact information

Jan Stålemark VD                               AroCell AB (publ)

jan.stalemark@arocell.com                Virdings allé 32B

0706-92 62 06                         754 50 UPPSALA

www.arocell.com                                 SVERIGE

 

 

Financial Calendar

02/22/2018 Interim report 4 – 2017

04/27/2018 Interim report 1 – 2018

15/06/2018 Annual General Meeting

08/31/2018 Interim report 2 – 2018

11/09/2018 Interim report 3 – 2018

 

 

Submission of interim report

 

Uppsala November 22, 2017

 

 

The board of directors

 

 

 

Summary Income statement
(TSEK) 2017 2016 2017 2016 2016
July-Sept July-Sept Jan-Sept Jan-Sept Jan-Dec
3 months 3 months 9 months 9 months full year
Net sales 46 293 46 59
Cost of goods sold -72
Selling expenses -974 -1,309 -4,656 -3,703 -5,020
Administrative expenses -646 -563 -2,335 -1,906 -2,193
Research and development expenses -2,058 -764 -4,740 -1,831 -2,075
Operating loss -3,678 -2,590 -11,510 -7,394 -9,229
Net financial items -1 -1 -6
Loss after financial items -3,678 -2,591 -11,510 -7,395 -9,235
Loss for the period -3,678 -2,591 -11,510 -7,395 -9,235
Summary balance sheet
(TSEK) 2017 2016 2016
30 Sept 30 Sept 31 Dec
ASSETS
Fixed assets
Intangible assets 30,209 29,206 31,328
Tangible assets 468 9 170
Financial assets 50
Total fixed assets 30,727 29,215 31,498
Current assets
Inventory 2,243 1,419 1,419
Other receivables 654 312 652
Cash and cash equivalents 20,196 39,021 32,852
Total current assets 23,093 40,752 34,923
Total assets 53,820 69,967 66,421
EQUITY AND LIABILITIES
Share capital 2,867 2,867 2,867
Restricted reserves 9,518 9,518
Other contributed capital and reserves 102,615 102,615 102,615
Non-restricted equity -63,054 -39,428 -51,544
Total equity 51,946 66,054 63,456
Current liabilities 1,874 3,913 2,965
Total equity and liabilities 53,820 69,967 66,421

 

 

 

 

Summary cash flow statement
(TSEK) 2017 2016 2017 2016 2016
July-Sept July-Sept Jan-Sept Jan-Sept Jan-Dec
3 mths 3 mths 9 mths 9 mths full year
Cash flow from operating activities -4,227 -784 -12,288 -3,285 -7,168
Cash flow from investing activities -2,376 -318 -7,396 -9,682
Cash flow from financing activities -50 0
Cash flow from the period -4,227 -3,160 -12,656 -10,681 -16,850
Cash and cash equivalents at beginning of period 24,423 42,181 32,852 49,702 49,702
Cash and cash equivalents at end of period 20,196 39,021 20,196 39,021 32,852
Share data 2017 2016 2016
Jan-Sept Jan-Sept Jan-Dec
Earnings per share (SEK) -0.40 -0.26 -0.32
Number of shares on balance sheet date 28,674,506 28,674,506 28,674,506

Interim report, Q3 2017

Delårsrapport Januari – Sept 2017

Abstract published presenting AroCell TK 210 ELISA from the PROMIX study at the European Society for Medical Oncology Congress in Singapore, November 17-19, 2017

AroCell AB (publ) announces today that the abstract entitled: “Quantification of cell loss in breast cancer during neoadjuvant treatment (NACT) assessed by serum thymidine kinase protein concentrations (sTK1)”, by B Tribukait et al was published today by the ESMO Asia congress organizers

https://cslide.ctimeetingtech.com/asia2017/attendee/confcal/session/calendar?q=Tribukait

The investigators quantified cell loss using the AroCell TK 210 ELISA kit to measure serum TK1 in serial samples from 145 breast cancer patients undergoing chemotherapy before surgery. Serum TK1 levels correlated to clinical/radiologically determined tumor response after cycles 2, 4 and 6, as well as pathologically determined response and disease-free survival. (To read the full abstract, please visit the ESMO Asia 2017 website.)

The investigators found that serum TK1 levels measured at the base-line and after completion of four cycles of treatment correlated significantly with clinical/radiological response during treatment and tumor-status at surgery. “This study shows that the reduction of tumor size and response to therapy can be assessed with our TK 210 ELISA” says Jan Stålemark, AroCell CEO. “Our product TK 210 ELISA was used in this study to investigate whether or not TK1 concentration can be a significant predictor of treatment response during chemotherapy of breast cancer. This is another study showing that serum TK1 measured with TK 210 ELISA is a promising biomarker for monitoring treatment response and possibly as a tool in clinical drug development. It gives a prompt signal on whether the new therapy works or not”.

 

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 09:30 CET on 08 November 2017.

About AroCell
AroCell AB (publ) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure Thymidine Kinase 1 (TK1) protein levels in a blood sample. The TK 210 ELISA test provides valuable information mainly about the condition of cancer patients. This may help clinicians to optimize treatment strategies and estimate the risk of recurrence of the tumor disease during the monitoring of the disease. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell’s Certified Adviser.

AroCell press release Final Nov 8 2017

AroCell AB: announces that a distribution agreement has been signed with Pathway Diagnostics Ltd, for distribution of the AroCell TK 210 ELISA test in United Kingdom and Ireland.

“We very much look forward to this new collaboration with the England based Pathway Diagnostics for the distribution of our TK 210 ELISA test”, states Jan Stålemark, AroCell CEO. “Pathway Diagnostics Ltd is a leading supplier of specialist clinical and research diagnostics in the UK and was established in 1998 to provide high quality in-vitro diagnostic products and instrumentation to clinical, research and industrial laboratories mainly in the UK and Ireland. Pathway Diagnostics are highly focused on the needs of their customers and in providing the highest quality products and service and therefore we consider them as a perfect match for our TK 210 ELISA test.”

The TK 210 ELISA test will be commercially available immediately through Pathway Diagnostics in the UK and Irish market.

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 08:50 CET on 13 October 2017.

About AroCell
AroCell AB (publ) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure (Thymidine Kinase 1 (TK1) protein levels in a blood sample. The TK 210 ELISA test provide valuable information mainly about the condition of cancer patients. This may help clinicians to optimize treatment strategies and estimate the risk of recurrence of the tumor disease during  monitoring of the disease. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell’s Certified Adviser.

Press Release Distribution UK20171011_final

AroCell Research Poster on TK1 / TK 210 ELISA in Prostate Cancer has been accepted for presentation at the UK National Cancer Research Institute (NCRI) Annual Meeting November 2017

AroCell AB (publ) announces today that a research poster submitted by Jagarlamudi K.K. et al. entitled ”AroCell TK 210 ELISA may complement pro PSA and the prostate health index in differentiating non-cancerous from cancerous conditions in prostate disease” has been accepted by the UK NICR for presentation at its annual meeting in November 5-8, 2017.

Thymidine kinase 1 (TK1) is a well-known cell proliferation biomarker. The purpose of this study was to compare the TK1 assayed with the AroCell TK 210 ELISA kit with PSA, free PSA, pro PSA and PHI (Prostate Health Index) in men with non-cancerous prostate conditions and patients with confirmed prostate cancer.

Serum samples with known PSA values from subjects investigated for prostate cancer were collected by the University Medical Centre, Ljubljana. Overall, AroCell TK 210 ELISA results showed significant correlation with PHI (r = 032, P = 0.0017) and pro PSA
(r = 021 P = 0.044) but not with free PSA or PSA. Combining the TK 210 value with the PHI or pro PSA value increased the diagnostic accuracy for prostate cancer compared with either individually.

CEO Jan Stålemark states “We are delighted that this preliminary study demonstrated that serum TK1 assayed with AroCell TK 210 ELISA kit can differentiate between non-cancerous conditions and prostate cancer patients with a similar accuracy to that of pro PSA or PHI. Further clinical studies will establish the capacity of AroCell TK 210 ELISA to complement pro PSA and PHI in distinguishing between non-cancerous and prostate cancer, potentially providing another tool in prostate cancer management”.

This data was previously presented at the American Academy for Cancer Research Annual Meeting April 2017.

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

 

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 11.00 CET on 26 September 2017.

 

About AroCell
AroCell AB (publ) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure (Thymidine Kinase 1 (TK1) protein levels, which provide valuable information about the speed of cell turnover. A tumor has high cell turnover (speed of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategy. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,600 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell’s Certified Adviser.

AroCell press release 26 Sept 2017

AroCell TK 210 ELISA abstract on in-vitro studies of cancer drugs has been accepted for presentation at the National Cancer Research Institute (NCRI) UK symposium

AroCell AB (publ) announces today that an abstract submitted Kiran Kumar Jagarlamudi et al entitled “The AroCell TK 210 ELISA provides new information concerning the mechanism of anti-cancer drugs by determining the TK1 protein levels in cultured cells in vitro” was accepted by the NCRI for presentation at their annual meeting in Liverpool, November 5-8, 2017.

The purpose of this study was to evaluate the capacity of TK 210 ELISA to measure TK1 levels in tumor cell culture models, using CEM lymphoblastic cells and Doxorubicin, which is an effective anti-neoplastic drug for both hematological and solid malignancies, and a commonly used chemotherapy drug. The conclusion in the study is that use of AroCell TK 210 ELISA provides opportunities for in-vitro studies of old and new anti-cancer drugs, targeting cell proliferation, which may assist in the development of new therapeutic agents.

“We are delighted over the results in this study and it is another piece of evidence that TK 210 ELISA will have a very broad applicability also in early stage drug development” states Jan Stålemark, CEO. “Controlling and/or inhibiting cell proliferation is an important parameter in early drug development and thus in the selection of drug candidates for cancer therapy. However, there are few cell-proliferation biomarkers which are suitable for large-scale use in in-vitro studies. This present work shows that TK1 levels in-vitro can be used to gain information on the effects of anti-cancer agents with tumor derived model cell lines. Furthermore, measuring the serum TK1 levels in patients with the TK 210 ELISA has been shown to provide clinically valuable information in a range of malignancies. This means that the assay of TK1 with the AroCell TK 210 ELISA test has the potential to enable routine application to drug discovery studies and in clinical trials. This potential is reinforced by another recent abstract on cell culture entitled Doxorubicin effects on leukemia and breast cancer cells in culture on the TK1 protein levels using AroCell TK 210 ELISA: a tool for drug development” says Jan Stålemark.

 

 

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

 

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 11.30 CET on 22 September 2017.

 

About AroCell

AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the rate of cell turnover. A tumor has high cell turnover (rate of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategies. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

AroCell press release Sept 22, 2017

New application for AroCell TK 210 ELISA opens new opportunities for drug development research

AroCell AB (publ) announces today that an abstract submitted by Kiran Kumar Jagarlamudi et al entitled “Doxorubicin effects on leukemia and breast cancer cells in culture on the TK1 protein levels using AroCell TK 210 ELISA: a tool for drug development” was accepted by the Purine and Pyrimidine Society for presentation at their annual meeting in Gdansk, Poland, September 20-24, 2017.

The purpose of this study was to evaluate the capacity of AroCell TK 210 ELISA to measure TK1 protein levels in cultured tumor cell lines. The effects of Doxorubicin on TK1 protein levels in extracts and media from CEM lymphoblastic cells as well as MDA-MB breast cancer cell cultures were studied for 24 hours. The results demonstrated that changes in intracellular and extracellular TK1 protein levels at different concentrations of DOX provide information about induction of TK1 in the cells, probably related to DNA damage, as well as release of TK1 protein into the media due to cytotoxicity.

“The results are very promising and demonstrate that AroCell TK 210 ELISA can be used to determine TK1 as a biomarker in in-vitro cell culture studies with drugs targeting cell proliferation and DNA repair. This means that our TK 210 ELISA test also has the potential to enable routine application in drug development studies” says Jan Stålemark AroCell CEO.

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 14:15 CET on 18 September 2017.

 About AroCell

AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the rate of cell turnover. A tumor has high cell turnover (rate of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategies. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

AroCell press release Sept 18, 2017

AroCell AB Interim Report, Q2 2017

AroCell AB (publ)
Reporting period 1 April – 30 June 2017

  • Net sales were 237 (0) KSEK
  • Losses after financial items were – 3,606 (- 1,962) KSEK
  • Earnings per share were – 0.27 (- 0.17) SEK
  • Cash flow from operating activities was – 3,163 (- 1,229) KSEK
  • Cash flow from investing activities was – 318 (- 1,800) KSEK

 

Interim report, 1 January – 30 June 2017

  • Net sales were 293 (0) KSEK
  • Losses after financial items were – 7,831 (- 4,804) KSEK
  • Earnings per share were – 0.27 (- 0.17) SEK

Revenues and expenses April – June 2017 (2016) KSEK

Sales for the period were 237 (0). Expenses were 3,771 (1,962). Taking into account capitalization of R&D, total expenses for the same period in 2016 amounted to 3,762. As the product has been fully developed and CE-marked, R&D expenses are no longer capitalized. According to plan marketing and sales expenses have increased which reflects our ambition to get TK 210 ELISA test to the market. Total cash flow for the period was -3,531 (-3,029). Cash at the end of the period was 24,423.

Revenues and expenses January – June 2017 (2016) KSEK

Sales for the period were 293 (0). Expenses were 8,052 (4,804). Taking into account capitalization of R&D, total expenses for the same period in 2016 amounted to 9,824. As the product has been fully developed and CE-marked, R&D expenses are no longer capitalized. According to plan marketing and sales expenses have increased which reflects our ambition to get TK 210 ELISA test to the market. Total cash flow for the period was -8,429 (-7,521). Cash at the end of the period was 24,423.

AroCell is obliged to make public this information pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication through Jan Stålemark, at 08:15 CET on 24 August 2017.

About AroCell
AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the rate of cell turnover. A tumor has high cell turnover (rate of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategies. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,500 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser. For the full Q2 Interim Report, please refer to the enclosed pdf file Interim report, Q2 2017

AroCell AB (publ) Interim report for period 1 January – 31 March 2017

AroCell AB (publ)

Interim report for period 1 January – 31 March 2017

  • Net sales were 56 (0) KSEK
  • Loss after financial items was – 4,225 (- 2,842) KSEK
  • Earnings per share were -0.15 (-0.10) SEK
  • Cash flow from operating activities was -4,898 (-1,272) KSEK
  • Cash flow from investing activities was 0 (-3,220) KSEK

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 08:25 CET on 11 May 2017.

 About AroCell
AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the speed of cell turnover. A tumor has high cell turnover (speed of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategy. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,600 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

 

Significant events during the reporting period

  • A scientific poster showing the correlation between TK 210 ELISA and Prostate Health Index (PHI) was accepted by AARC, American Association of Cancer Research.
  • AroCell participated at the World Biomarker Congress in Manchester, UK in February.
  • A webinar entitled “Improved Monitoring of Tumor Growth with a Novel Serum Proliferation Biomarker” was held on March 23rd, with 135 participants from both industry and academia.

 

Significant events after the reporting period

  • AroCell attended the AACR congress in Washington, DC together with its distribution partner Eagle Biosciences.
  • The Biomarker and World Congress in Philadelphia on May 2-4.

Comments by CEO Jan Stålemark

A key priority for Arocell in 2017 is to ensure that we have a strong strategic framework in place to maintain focus for our activities and drive commercial growth. We have identified key areas where we will focus on moving forward which include elements to support both the commercial and clinical strategies.

Our commercial activities have increased significantly during the last period. We have seen a very positive response to our diverse marketing activities. These activities have generated significant interest in our product, providing plenty of contacts and leads for us to follow up on. We are thereby now able to make advances in commercializing our CE-marked TK 210 ELISA kit into the clinical research market.

The clinical validation is a key focus to ensure customer acceptance for long term growth. We have made good progress in the clinical development plans and expect to be presenting preliminary and interesting results soon. The Swedish Promix multicentre study has been analysed and publication is planned. Both our prospective studies, Sarcoma at Helsinki hospital and Prostate cancer at the South Hospital in Stockholm are on plan and expected to be completed by the end of 2018. We have also completed the analysis of the biobank samples in the U-CAN study in Uppsala. The remaining work is to get the results analysed in correlation to the patient records which will be done by the clinicians at Uppsala Academic Hospital. This is key to our strategy in obtaining clinical acceptance through clinical validation, in order to introduce our product to the global in vitro diagnostic market.

As prostate cancer is a key component in our clinical development program, it is essential to communicate the results to the medical community. A scientific poster was presented at the AARC, American Association of Cancer Research. It shows significant correlation between results by TK 210 ELISA and Prostate Health Index (PHI), a new index to determine patient status for individuals with suspected or confirmed prostate cancer. The study compare AroCell’s TK 210 ELISA test with other commonly used test methods such as PSA, free PSA, pro PSA and PHI in men with pre-cancerous conditions and confirmed prostate cancer indicates that AroCell’s TK 210 ELISA test provides valuable clinical information.

We have the only CE-marked kit on the market that measures concentrations of TK 1 protein in serum from a simple blood test based on the global standardized ELISA format. Our product’s uniqueness has generated interest well above our expectations during meetings with potential customers from the research and medical communities at trade shows and conferences. This will be a strong basis to find new partners and markets in 2017.

With a robust product, commercially available and with an increased customer interest, we are now putting full efforts behind our plans for launching the TK 210 ELISA kit into the clinical research market as well as the ongoing clinical development program.

Jan Stålemark

CEO

 For the full interim report please see the enclosed pdf:
AroCell Q 1 2017 report FINAL

AroCell AB (publ) Year-End Report

 

 

AroCell AB (publ) Year-End Report

Report for period 1 January – 31 December 2016

  • Net sales were 59 (0) KSEK
  • Loss after financial items was 9,235 (-7,479) KSEK
  • Earnings per share were -0.32 (-0.26) SEK
  • Cash flow from operating activities was -7,168 (-9,127) KSEK

 

Reporting period 1 October – 31 December 2016

  • Net sales were 13 (0) KSEK
  • Loss after financial items was -1,840 (–1,622) KSEK
  • Cash flow from operating activities was -3,882 (-2,442) KSEK
  • Work was initiated to construct a company-owned laboratory for product development use as well as customer support and service.

 

  • Ann Hammarstrand was appointed as new CFO and Kris Rydholm Överby was appointed PR/Marketing Communication Manager.

 

 For the full report in PDF, please look below.


This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 08:15 CET on 16 February 2017.

About AroCell
AroCell AB (AROC) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the speed of cell turnover. A tumor has high cell turnover (speed of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategy. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,600 shareholders.  For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

 

AroCell Year End Report 2016 Eng

AroCell research poster on prostate cancer has been accepted by American Association for Cancer Research (AARC)

AroCell AB (publ) announces today that a research poster submitted by Kiran Kumar J et al entitled ”The AroCell TK 210 ELISA may complement Pro PSA and the Prostate Health Index in differentiating pre-cancerous and cancerous conditions in prostate cancer” was accepted by the AARC for presentation at their annual meeting in April 2017.

The purpose of this study was to compare the AroCell TK 210 ELISA with PSA, free PSA, pro PSA and PHI (prostate health index) in men with pre-cancerous conditions and patients with confirmed prostate cancer.

Serum samples from 94 patients with known PSA values for prostate cancer were collected by the University Medical Centre, Ljubljana. Overall, the AroCell TK 210 ELISA showed significant correlation with PHI (r=032, P=0.0017) and pro PSA (r021 P=0.044) but not with free PSA or PSA.

CEO Jan Stålemark states “We are delighted that this preliminary study demonstrates that serum TK1 assayed with AroCell TK 210 ELISA can differentiate between pre-cancerous conditions and prostate cancer patients with a similar accuracy to that of pro PSA.  Further clinical studies will establish the capacity of AroCell TK 210 ELISA to complement pro PSA and PHI in distinguishing between pre-cancerous and prostate cancer, potentially providing another tool in prostate cancer management”.

 

For additional information:
Jan Stålemark, CEO
AroCell AB (publ)
Tel: +46(0)706926206
info@arocell.com
www.arocell.com

 

This information is information that AroCell is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Markets Act. The information was submitted for publication, through Jan Stålemark, at 11:45 CET on 24 January 2017.

 

About AroCell
AroCell AB (publ) is a Swedish company that develops standardized modern blood tests to support the prognosis and follow up of cancer patients. AroCell’s new technology is based on patented methods to measure TK1 protein levels, which provide valuable information about the speed of cell turnover. A tumor has high cell turnover (speed of cell division and cell death) and as a result TK1 can be detected in the blood with a simple laboratory test, called TK 210 ELISA. The test provides valuable clinical information for prognosis and optimization of treatment strategy. The test may also be used for monitoring disease relapse. AroCell (AROC) is listed at Nasdaq First North and has about 2,600 shareholders. For more information, please see www.arocell.com. Redeye AB is AroCell:s Certified Adviser.

AroCell Press Release Jan 24, 2017