In-Vitro studies of cell proliferation and TK 210 ELISA as a translational biomarker

Thymidine Kinase 1 (TK 1) is a sensitive cell proliferation biomarker that has been used widely to study malignancies in-vivo, but technical difficulties in current assays have restricted its use. Controlling and / or inhibiting cell proliferation is an important goal of cancer therapy.

Studying this parameter early in the drug development process can aid in the selection of drug candidates, but there few cell-proliferation biomarkers suitable for large-scale use in in-vitro studies.

The assay of TK1 in cell culture using AroCell TK 210 ELISA opens the opportunity for the study of a new important parameter in drug development.